Introduction of Circos
Circos is a software package for visualizing data and information. With its unique display layout, it is an ideal tool for exploring the relationship between objects and positioning. The Circos diagram can be used to conveniently display various types of information, and is particularly suitable for displaying different levels of data information in the form of Circos circles. Due to these advantages, it is often used in different fields to present data analysis results. In the field of life sciences, Circos diagrams were originally used to visualize genomic sequence-related data. It has been expanded to many other fields, such as the enrichment of metabolic pathways, species diversity and genome coverage. In short, most relational data can be visualized with Circos.
Circos is easy to plot, format and layer data. A large variety of plot and feature parameters are customizable to create images that best communicate your data. After supplying data to Circos as plain-text files and inputting the ideal plot using the configuration file, the image can then be created.
Fig 1. Copy number whole-genome profiles of five follicular lymphoma tumor samples generated from the Affymetrix Mapping 500K array. ( Krzywinski M, et al., 2009 )
Application Field
Cancer genomics.
Comparative genomics.
Molecular biology.
Whole genome copy number map analysis.
Systems biology analysis.
Tabular data visualization.
The circos software package can be used in a variety of biological information data analysis scenarios, and the generated pictures are clear and intuitive. As long as you have a certain basis of bioinformatic analysis, Circos is easy to learn. But if you are restricted in time and energy for learning this new tool and still want to present your research results through Corcos diagrams, you can contact us at any time. CD Genomics has a professional biological information analysis team. Once receiving the original data from you, we will provide you with biological data analysis and make charts. We look forward to working with you!
Reference
- Krzywinski M, et al. Circos: an information aesthetic for comparative genomics. Genome Res. 2009;19(9):1639-1645. doi:10.1101/gr.092759.109.
