CD Genomics can use GO enrichment analysis to classify differential genes and other genes by GO and perform significance analysis, misclassification rate analysis, and enrichment analysis based on discrete distributions on the classification results to help customers obtain the functional classification of genes that are significantly associated with research objectives with low misclassification rate and targeting.
Introduction of GO Enrichment Analysis
Gene ontology is one of several biological ontology languages that provide a three-level structured approach to the definition of systems for describing the function of gene products. The first level is the cellular component, which mainly explains where the gene is present. The second level is the biological process, which mainly explains which biological processes the given gene is involved in. The third level is the molecular function, which mainly explains what the function of the gene is at the molecular level and what reactions it catalyzes.
Figure 1. Functional enrichment analysis of DEGs. (Li H, et al., 2019)
Applications
GO enrichment analysis can be used for but is not limited to the following research:
- Used for analysis to identify key genes and pathways of disease.
- For the exploration of functional pathways related to the prognostic gene signature of diseases.
- For exploring the pathogenesis of diseases.
Deliverables
- Bubble diagram of the results of enrichment analysis of biological processes, molecular functions, and cellular components.
- Bar graph of the results of biological process, molecular function, and cellular component enrichment analysis.
- GO enrichment analysis results table.
- GO enrichment analysis string diagram.
CD Genomics GO Enrichment Analysis Pipeline
GO Enrichment Analysis Content
- We are able to provide GO enrichment analysis services for our customers using tools such as topGO, Bingo, Agrigo, etc.
- We are able to plot different GO enrichment results to provide different visualization solutions for our customers.
- We can help our customers select the appropriate set of genes to screen for functional changes relevant to the subject according to the purpose of the study.
We are able to use GO enrichment analysis services to help our customers achieve high throughput data analysis in multi-omics. For questions about analysis content, project cycle, and pricing, please click online inquiry.
How It Works
CD Genomics is a professional bioinformatics service provider with years of experience in NGS and long-read sequencing (PacBio SMRT and Oxford Nanopore platforms) data, proteomics and metabolomics data analysis, integrated analysis services, database construction, and other bioinformatics solutions.
CD Genomics has professional bioinformatics experts who have successfully provided GO enrichment analysis services to researchers in many different fields. Our professional skills and enthusiasm will provide you with high-quality analysis services. If you are interested in our services, please contact us for more details.
Reference
- Li H, et al. Transcriptomic analysis and identification of prognostic biomarkers in cholangiocarcinoma. Oncol Rep. 2019 Nov; 42(5): 1833-1842.
