CD Genomics, as one of the few exosomal RNA data analysis providers, relies on rich experience in RNA projects and leading bioinformatics analysis strength to provide customers with system solutions for exosomal RNA research, helping you to carry out in-depth identification and functional analysis of exosomal mRNA, miRNA, lncRNA, etc. If we are fortunate to cooperate, we will provide you with a high-quality data analysis platform, a fast analysis cycle and a high-quality result report.
Introduction of Exosomal RNA Sequencing
Exosome is a kind of tiny membrane vesicles secreted by most cells, which is distributed in peripheral blood, urine, saliva, ascites, amniotic fluid and other body fluids. The contents of exosome include proteins, lipids and nucleic acids, as well as various types of non-coding RNA (including miRNA, lncRNA, circRNA, etc.). Its contents, such as miRNA, can be swallowed by other cells and become an important medium for cell-to-cell communication. More and more evidence shows that exosomes secreted by host cells or tumor cells are involved in tumorigenesis, growth, invasion and metastasis. Because the detection of molecular markers in body fluids such as peripheral blood is non-invasive and repeatable, multiple indexes can be detected at the same time. Therefore, the study of exosome is of great significance to the diagnosis of diseases.
Through high-throughput sequencing of exosomal RNA and bioinformatics analysis, we can quickly and efficiently obtain comprehensive information of exosomal RNA, such as the analysis of miRNA, lncRNA, circRNA, a promising molecular marker for clinical diagnosis, which is an ideal method for disease diagnosis and follow-up. Exosome can be associated with almost any disease, and has become a hot spot of innovation in disease markers, disease mechanism, drug development and other research.
Fig 1. Bystander autophagy induced by the exosomal miR-7-5p in recipient BEP2D cells. (Song M, et al, 2016)
Applications
Molecular marker analysis, typing and staging study.
The study of disease mechanism, the occurrence, development and metastasis of disease, and the study of tumor microenvironment.
Clinical disease monitoring, auxiliary diagnosis, prognosis follow-up.
Research and development of drug carriers.
Technological Advantages
Rich experience in exosomal RNA sequencing data analysis.
The data analysis plan can be customized according to actual needs.
Strict data analysis process and strict data quality control ensure accurate and reliable data analysis results.
Customized charts can be used directly for article writing.
Fast analysis cycle can speed up your research progress.
CD Genomics Analysis Pipeline
Fig 2. Pipeline of exosomal RNA data analysis.
Bioinformatics Analysis Content
CD Genomics has a wealth of experience in RNA data analysis, which can meet the data analysis needs of different exosomal RNA sequencing solutions. Such as the analysis of different exosomal RNA sequencing programs-mRNA, lncRNA, miRNA and other sequencing data. The following is the analysis content of exosomal miRNA sequencing data
| 1. Sequencing data statistics |
2. Data quality control |
| 3. High quality data acquisition |
4. Rfam database comparison |
| 5. Repbase database comparison |
6. Clean small RNA length distribution |
| 7. miRNA detection and discovery, and detection rate statistics |
8. miRNA length distribution |
| 9. Differential expression analysis |
10. Differentially expressed genes GO and KEGG enrichment analysis |
| 11. SNP and indel analysis |
12. Alternative splicing analysis |
| 13. Visual analysis |
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For exosomal RNA sequencing data analysis, we will provide suitable data analysis solutions according to your different exosomal RNA sequencing solutions. For the analysis content, project cycle and price, if you have any questions, please click online inquiry.
How It Works
CD Genomics is a high-tech company specializing in multiomic data analysis. We provide services such as project design, data analysis, and database construction. With a focus on developing breakthrough products and services, we are a pioneer in the biotechnology industry, serving researchers and partners worldwide.
Bioinformatics-Analysis, a division of CD Genomics, has successfully conducted exosomal RNA data analysis on a variety of samples, combined with rich project experience, professional project plan guidance and analysis process, to ensure that the project is carried out accurately and quickly. Please contact us for more information and a detailed quote.
Reference
- Song M, et al, Bystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cells[J]. Scientific Reports. (2016) 6:30165.
