CD Genomics is able to provide customers with volcano plot services that enable visual analysis of genomics, transcriptomics, proteomics, and metabolomics data.
Introduction of Volcano Plot
A volcano plot is a scatter plot that combines p-values from statistical tests with variation recurrence, designed to help clients quickly and visually identify data points with large and statistically significant variation recurrence. With the rapid development of bioinformatic, or supra graphs are often used for data statistics in genomics, transcriptomics proteomics, and metabolomics.
The volcano plot is a visualization of the results of the different analyses. The larger the absolute value of the horizontal coordinate in the volcano plot, the greater the difference between the two subgroups, and the larger the value of the vertical coordinate, the more significant the difference in gene expression between the subgroups and the more reliable the results.
Figure 1. Differential metabolite identification for the experimental dataset using CVP, and RVP. (Kumar N, et al., 2018)
Application Field
Volcano plots can be used for but are not limited to the following research:
- Screening for differentially expressed genes in the development of biomarkers for poor disease prognosis.
- Volcano plots can be combined with liquid chromatography-mass spectrometry to reveal the etiology of the disease.
- For transcriptomics and proteomics studies.
- Volcano plots are used to visualize and explore high-throughput data.
CD Genomics Volcano Plot Service Pipeline
Volcano Plot Service Content
- We are able to help our customers personalize parameters such as color, shape, size, wrap-around, and shadow of the volcano plot.
- We can help our customers to insert gene names in the volcano plot to avoid data overlap.
- We provide the complete conclusion based on the analysis of the volcano map.
We are able to use volcano plot services to help our customers achieve high throughput data analysis in genomics, transcriptomics, proteomics, and metabolomics. For questions about analysis content, project cycle, and pricing, please click online inquiry.
How It Works
CD Genomics is a professional bioinformatics service provider with years of experience in NGS and long-read sequencing (PacBio SMRT and Oxford Nanopore platforms) data analysis, integrated analysis services, database construction, and other bioinformatics solutions.
CD Genomics has professional bioinformatics experts who have successfully provided volcano plot services to researchers in many different fields. Our professional skills and enthusiasm will provide you with high-quality analysis services. If you are interested in our services, please contact us for more details.
References
- Kumar N, et al. Robust volcano plot: identification of differential metabolites in the presence of outliers. BMC Bioinformatics. 2018 Apr 11; 19(1): 128.
- Yang MT, et al. Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach. Front Endocrinol (Lausanne). 2021 Apr 28; 12: 641336.
