As one of the providers of genotyping analysis, CD Genomics uses bioinformatics to help you quickly locate mutations and explore genetic variations. Our unique data analysis skills and appropriate software can meet customers' personalized laboratory data analysis needs and provide easy-to-interpret data analysis reports.
Introduction of Genotyping Analysis
Genotyping is the process of using biological experiments to examine an individual's DNA sequence, and comparing the target sequence with another individual's sequence or reference sequence to determine individual genetic composition (genotype) differences.
Genotyping helps determine differences in the individual's genetic makeup, such as single nucleotide polymorphisms (SNPs) and large structural changes in DNA. Genotyping analysis plays an important role in research of genes and gene variants associated with disease. Next-generation sequencing (NGS) and microarrays enable a deeper understanding of disease etiology on a molecular level. With multiple genomic targets potentially contributing to disease, analysis requires flexibility and accuracy. SNP genotyping and copy number variation (CNV) data analysis tools can analyze results for millions of markers and probes and detect sample outliers, providing insight into the functional consequences of genetic variation. SNP genotyping is also used in many scientific disciplines including personalized medicine, plant and animal biotechnology.
Fig 1. SNP Genotyping data analysis using nanofluidic Dynamic Arrays.(Wang J; et al.2009)
We Can Help Our Clients With
1.Large-scale genome-wide association analysis.
2.Research on disease susceptibility loci and susceptibility genes.
3.Animal and plant variety breeding.
4.Population genetics research.
5.Pharmacogenomics.
6.Diagnostics.
CD Genomics Genotyping Analysis Pipeline
The type of original input data can be different type of microarrays chip data, and next-generation sequencing data such as whole genome sequencing data, whole exome sequencing data and so on. Genotyping results of microarrays chip data are generally generated by the chip company. The following pipeline shows the analysis of genotyping using whole genome sequencing data.
What We Offer
Genotyping bioinformatic analysis includes (Whole genome sequencing data or whole exome sequencing data) data quality control, variation analysis and so on.
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Standard analysis
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Quality control of sequencing data
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Map to reference genome
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SNP detection and annotation
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CNV detection and annotation
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Indel detection
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For genotyping analysis, regardless of whether your input data type is sequencing data or microarrays chip data, if you have personalized customization analysis needs, we will provide appropriate biological information analysis content according to your needs, please feel free to contact us for details.
How It Works
CD Genomics is a high-tech company specializing in multiomic data analysis. We provide services such as project design, data analysis, and database construction. With a focus on developing breakthrough products and services, we are a pioneer in the biotechnology industry, serving researchers and partners worldwide.
Combining rich project experience, professional project plan guidance, and analysis process, CD Genomics has successfully conducted genotyping analysis on a variety of diseases, animals and plants. We ensure that the project is carried out accurately and quickly. Please contact us for more information and a detailed quote.
Reference
- Wang J; et al. High-throughput single nucleotide polymorphism genotyping using nanofluidic Dynamic Arrays[J]. BMC Genomics, 2009, 10(1):561.
