The Venn diagram is an illustration used to show the overlapping area of the element collection. It is a graph that uses a fixed position of a cross-loop to express the collection and its relationship with a closed curve. In life science research, the Venn diagram can be used to count the number of common or unique elements (such as genes, species, functions, OTUs) between multiple samples or multiple groups. It can intuitively reflect the similarities and differences in element composition between different samples. Venn diagrams can generally be used to analyze the similarity and overlap of 2-5 samples or 2-5 groups. The circles in different colors in the figure represent samples or groups under different environments or conditions. The number marked in the overlapping area in two different colored circles represents the number of the same elements in the two samples, and the number marked in the non-overlapping area represents the number of unique elements in the two samples.
Venn diagrams can be produced by different software, such as simple excel, professional VENN diagram production software, and R language limma package, gplots package, venneuler package and VennDiagram package, et al.
Fig 1.Venn diagram illustrating shared and unique gene families (gene numbers in parenthesis) among the five grass species including T. urartu, rice, maize, sorghum and B. distachyon. (Ling H Q , et al. 2013)
The following are some application scenarios of the VENNE diagram:
Gene differential expression analysis.
Analysis of differences between species.
VENN diagram is a common and intuitive data analysis presentation, and it can be created easily through different software. However, if your original data volume is particularly large or you have high requirements on presenting the VENN diagram, professional bioinformatics analysis software and skills would be preferred. CD Genomics has a professional biological information analysis team. Provide the data and we will constructure the VENN diagrams for you. Contact us at any time.