The Venn diagram is an illustration used to show the overlapping area of the element collection. It is a graph that uses a fixed position of a cross-loop to express the collection and its relationship with a closed curve. In life science research, the Venn diagram can be used to count the number of common or unique elements (such as genes, species, functions, OTUs) between multiple samples or multiple groups. It can intuitively reflect the similarities and differences in element composition between different samples. Venn diagrams can generally be used to analyze the similarity and overlap of 2-5 samples or 2-5 groups. The circles in different colors in the figure represent samples or groups under different environments or conditions. The number marked in the overlapping area in two different colored circles represents the number of the same elements in the two samples, and the number marked in the non-overlapping area represents the number of unique elements in the two samples.
Venn diagrams can be produced by different software, such as simple excel, professional VENN diagram production software, and R language limma package, gplots package, venneuler package and VennDiagram package, et al.
Fig 1.Venn diagram illustrating shared and unique gene families (gene numbers in parenthesis) among the five grass species including T. urartu, rice, maize, sorghum and B. distachyon. (Ling H Q , et al. 2013)
The following are some application scenarios of the VENNE diagram:
Gene differential expression analysis.
Analysis of differences between species.
VENN chart is a very common and intuitive data analysis presentation form, and it can be created very easily through different software. However, if your original data volume is particularly large or you have high requirements for the presentation of the VENN chart, you need professional bioinformatics analysis software and professional analysis skills to complete it. If you do not have enough time and experience to complete the complicated VENN diagram, then you can contact us at any time. CD Genomics has a professional biological information analysis team, you only need to provide the original data, we will provide you with exquisite VENN diagrams and diagram interpretation files. If we are lucky enough to cooperate, we will serve you wholeheartedly!