CD Genomics provides global bioinformatic analysis service. We use advanced analysis methods to analyze small RNA sequencing data, and can quickly identify and predict various types of small RNA at the genome-wide level to obtain all genes related to regulation.
Small RNA refers to endogenous RNA with a length of 18 to 30 nt, including miRNA, siRNA and piRNA. They play an important role in the regulation of mRNA transcription and post-transcription levels, participating in various biological processes such as cell growth, differentiation, and metabolism. The function of small RNA in the normal development of the organism and the disease process is also vital.
Small RNA sequencing data analysis refers to the large-scale detection of small RNAs of target samples based on high-throughput sequencing platforms, combined with bioinformatics mining, to conduct a comprehensive analysis of miRNA, siRNA, piRNA in samples. This type of analysis can identify known small RNA, predict new small RNA and predict the target genes of small RNAs, providing a powerful means for studying the function, structure and regulatory mechanism of small RNA.
Fig 1. Differentially expressed miRNAs in colorectal cancer samples (p<0.05). (Srinivas V K, et al. 2017)
Animal and Plant Research
Molecular diagnostic testing
Rich experience in small RNA analysis sequencing data analysis.
Reliable analysis results.
Flexible custom analysis
CD Genomics uses authoritative algorithms in academia to systematically classify and annotate miRNA, siRNA, piRNA, and unknown small RNA, and then fully explore the regulatory functions of small RNA through base editing analysis, expression level analysis, and target gene prediction.
|Data preprocessing||Sequencing data statistics|
|Remove adapter sequence and low-quality sequence|
|Statistical data output|
|Assess the quality of sequencing|
|Map to reference genome||Statistical comparison rate|
|Small RNA identification||Screen and identify miRNA, siRNA, piRNA|
|Screen and identify new sRNA|
|Sequence analysis||Distribution of Small RNA on selected reference genomes|
|Comparison of Small RNA and exon/intron|
|miRNA seed sequence analysis|
|Differential expression analysis||MiRNA difference analysis between samples|
|Differential miRNA cluster analysis|
|MiRNA target gene analysis||MiRNA target gene prediction|
|MiRNA target gene GO annotation analysis|
|MiRNA target gene KEGG pathway analysis|
For small RNA sequencing data analysis, if you have other sequencing data, such as circular RNA sequencing data, we can provide you with interaction analysis of miRNA and circular RNA based on your data. If you have other analysis needs, we will negotiate and determine the most suitable analysis content based on your data and needs. For analysis content, price, cycle, if you have any questions, please click online inquiry.
CD Genomics is a professional bioinformatics service provider with years of experience in NGS and long read sequencing (PacBio SMRT and Oxford Nanopore platforms) data analysis, integrated analysis services, database construction and other bioinformatics solutions.
CD Genomics has successfully conducted small RNA sequencing data analysis on a variety of species. Experienced teams of scientists, researchers, and technicians, we provide fast turnaround, high-quality data reports at competitive prices for worldwide customers. Customers can contact our employees directly and we will respond promptly. If you are interested in our services, please contact us for more detailed information.