CD Genomics is based on a mature high-throughput sequencing platform, combined with epigenetics research methods, to provide you with a variety of apparent level biological information analysis services, such as genome-wide epigenetic positioning analysis and genes Research on expression regulation mechanism. We will provide you with a clear and reliable report of epigenetic information analysis results.
Epigenetic modifications are reversible modifications that affect gene expression without altering the DNA sequence and can be inherited during cell division. Two of the most characterized epigenetic modifications are DNA methylation and chromatin modification. Epigenetic modifications play important roles in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation, development and tumorigenesis. DNA methylation is most frequently observed at the C5 position of cytosine followed by guanine (CpG site) in vertebrates, or non-CpG sites such as CHG and CHH in plants or mammalian embryonic stem cells. DNA methylation is established and maintained by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b).
At present, epigenetic bioinformatics analysis mainly focuses on DNA methylation and histone modification. The study of apparent level shines brilliantly in disease research and has become a research hotspot.
It is the basis of epigenetics research to mine key information from sequencing data of epigenetics through bioinformatics. CD Genomics analysis team not only provides standardized biological information analysis content, but also provides personalized customized analysis services according to customer project needs. For epigenetic bioinformatics analysis, if you have other types of epigenetics sequencing data analysis needs, we will formulate corresponding analysis strategies according to your needs. If you are interested in our services, please feel free to contact us for more information.