CD Genomics uses a mature high-throughput sequencing platform combined with epigenetics to provide a variety of biological information analysis services, such as genome-wide epigenetic positioning analysis and genes research on expression regulation mechanism. We will provide you with a clear and reliable report of epigenetic analysis result.
Epigenetic modifications are reversible modifications that affect gene expression without altering the DNA sequence and can be inherited during cell division. Two of the most characterized epigenetic modifications are DNA methylation and chromatin modification. Epigenetic modifications play important roles in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation, development and tumorigenesis. DNA methylation is most frequently observed at the C5 position of cytosine followed by guanine (CpG site) in vertebrates, or non-CpG sites such as CHG and CHH in plants or mammalian embryonic stem cells. DNA methylation is established and maintained by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b).
At present, epigenetic bioinformatic analysis focuses on DNA methylation and histone modification. The study of apparent level takes an important seat in disease research.
It is the basis of epigenetic research to mine key information from sequencing data of epigenetics through bioinformatics. CD Genomics' analysis team not only provides standardized biological information analysis content, but also provides personalized customized analysis services according to customer project needs. If you are looking for epigenetics sequencing data analysis, we will formulate corresponding analysis strategies accordingly. Please feel free to contact us for more information.